Nitrile Functional Group Molecule Structure

SKU: 68845NV

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Investigate the nitrile functional group with Orbit molecular models. Learn about key compounds, chemical reactivity, biological roles, and more as they relate to chemical & biological applications.

Nitriles are organic compounds containing the carbon–nitrogen triple bond (–C≡N), a functional group important in both synthetic organic chemistry and biochemical contexts. In chemistry, nitriles are studied for nucleophilic addition, hydrolysis to carboxylic acids, and their role as versatile intermediates in the preparation of amides, amines, and heterocycles. In biology and medicine, nitrile-containing molecules occur in pharmaceuticals, natural products, and metabolic intermediates. Orbit nitrile molecular models allow students to visualize linear geometry, triple-bond electron density, and functional group interactions, making them valuable tools for chemistry majors and biology, nursing, or premed students.

Indigo Instruments has held inventory of genuine Cochranes of Oxford (Orbit) atoms & bonds for 30+ years. These parts are compatible with every molecular model set we have sold since day 1. This quality may appear expensive but no parts support from other vendors costs even more.

Details

Key Nitrile Functional Group Examples for the Classroom

 
Compound Chemistry Use Case Biology / Medicine Relevance
Acetonitrile Solvent and simple aliphatic nitrile for studying nucleophilic addition and hydrolysis reactions. Used in laboratory extractions; illustrates safety considerations.
Benzo­nitrile Aromatic nitrile; demonstrates electronic effects in addition reactions and aromatic reactivity. Present in some plant metabolites; model for bioactive aromatic nitriles.
Cyanoalanine Shows nitrile in amino acid derivatives; studies enzyme-mediated transformations. Intermediate in cyanogenic metabolism; relevant for understanding detoxification.
Rilpivirine Pharmaceutical nitrile; illustrates structure–activity relationships in drug design. Antiretroviral drug; demonstrates medicinal chemistry applications.
Malononitrile Active methylene compound; condensation reactions and Knoevenagel mechanisms. Model for enzyme mimic studies; limited direct biological occurrence.
 

The 68845NV basic set includes 16 carbons and 18 hydrogens but only 2 of the tetrahedral nitrogens (blue) and 6 of the 50mm white bonds, so only 2 of the 3 nitriles shown can be built simultaneously.

The nitrile molecular structures shown in the image are acetonitrile, acrylonitrile & cyanide shown from left to right clockwise. Build these & other alcohols with the Indigo® Instruments 3D Molecular Model Builder

 

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Reviews (5)
2020-09-10
This model kit is great for improving knowledge of molecular structures for organic chemistry.
— Jan
2020-05-31
I bought the product for a university class and it met expectations. Great service and fast shipping.
— Miri
— Indigo: Thank you for the review. Good luck this term.
2019-09-23
Great product, fast shipping, excellent customer service!
— Courtney
2019-08-15
Bought two of these because I prefer them to the one used at the university. Easy to use and has a good flexibility.
— Thierry
2018-04-16

I've had consistently great service from this company. Our students seem to really appreciate the reasonable price. In the years that we've used this product, not one has been returned due to defects.

— Becki
— Indigo:

Considering how many of these we sell to schools every year, that is high praise indeed. Thanks letting us know.

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