Paraxanthine

https://pubchem.ncbi.nlm.nih.gov/compound/Paraxanthine https://hmdb.ca/metabolites/HMDB0001860 reference for purines. https://en.wikipedia.org/wiki/Paraxanthine but not much there.

Paraxanthine is often taken as a supplement to coffee for its stimulant affect. This raises the question of what does paraxanthine do in the body? Paraxanthine can stimulate lipolysis which is the breakdown of fat stored in adipose tissue. This is believed related to the cyclic AMP (cAMP) signalling pathway in adipocytes (fat cells) which releases fatty acids into the bloodstream. Paraxanthine increases energy expenditure (calorie burning) for improved stamina & weight loss, increased alertness and improved cognitive function. Like caffeine, paraxanthine has diuretic properties which contribute to mild dehydration.

An unusual but useful medical application is as a biomarker that can identify people who could response positively to platinum-based chemotherapy protocols.

A molecular model of Paraxanthine in the Molymod Hybrid Dome style uses the atoms & bonds in the parts list below. Our free 3D Molecular Model Builder shows other styles & allows for image rotation as an assembly guide.

Chemical data
Molecular Weight Chemical Formula
180.1658 C7H8N4O2

Paraxanthine molecular model built with Molymod Atoms & Bonds

Parts
P/NDescriptionQTY
60150EAtom, Molymod, white (hydrogen), hemisphere, 19mm8
60200EAtom, Molymod, red (oxygen), 2 hole, 105 degrees2
60311EAtom, Molymod, blue (nitrogen), 3 hole, 120 degrees, 23mm3
60400EAtom, Molymod, black (carbon), 4 hole, 109.5 degrees, 23mm7
60401EAtom, Molymod, blue (nitrogen), 4 hole, 109.5 deg., 23mm1
61012EBond, Molymod, grey (single), 20mm10
61013EBond, Molymod, grey (double/triple), 35mm8
61015EBond, Molymod, opaque, 2mm (for spacefilling models)8
Synonyms
  • IUPAC Name: 1,7-dimethyl-3H-purine-2,6-dione
  • InChI=1S/C7H8N4O2/c1-10-3-8-5-4(10)6(12)11(2)7(13)9-5/h3H,1-2H3,(H,9,13)
  • InChIKey: QUNWUDVFRNGTCO-UHFFFAOYSA-N
  • SMILES: CN1C=NC2=C1C(=O)N(C(=O)N2)C
  • CAS: 611-59-6
  • 1,7-Dimethylxanthine
  • 1H-Purine-2,6-dione, 3,7-dihydro-1,7-dimethyl- (9CI)
  • 3,7-Dihydro-1,7-dimethyl-1H-purine-2,6-dione