Metformin (Dimethylbiguanide)

Construct a chemical structure model of the diabetes drug Metformin (Glucophage) from Genuine Molymod Atoms & Bonds by Indigo

Metformin is an oral medication prescribed for type 2 diabetes. Its chemical structure is classed as a biguanide which consists of consists of two amidine (NH=C(NH2)) groups. Metformin is a first-line treatment for type 2 diabetes since it lowers blood glucose levels by targeting receptors in liver and muscle tissue. Metformin's mechanism of action is believed to target cell metabolism by improving glycemia. It lowers glucose levels by inhibiting liver gluconeogenesis as well as opposing action by the hormone glucagon. It may act on AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms & inhibition of mitochondrial glycerophosphate dehydrogenase.

A molecular model of Metformin in the Molymod Hybrid Dome style uses the atoms & bonds in the parts list below. Our free 3D Molecular Model Builder shows other styles & allows for image rotation as an assembly guide.

Chemical data
Molecular Weight Chemical Formula
165.6253 C4H12ClN5

Metformin (Dimethylbiguanide) molecular model built with Molymod Atoms & Bonds

Hybrid Dome
62053
Open Sphere
62009
Orbit Basic
68845NV
Orbit Flexible
68827W 68847W
Parts Synonyms
Parts
P/NDescriptionQTY
60150EAtom, Molymod, white (hydrogen), hemisphere, 19mm11
60311EAtom, Molymod, blue (nitrogen), 3 hole, 120 degrees, 23mm3
60400EAtom, Molymod, black (carbon), 4 hole, 109.5 degrees, 23mm4
60401EAtom, Molymod, blue (nitrogen), 4 hole, 109.5 deg., 23mm2
61012EBond, Molymod, grey (single), 20mm6
61013EBond, Molymod, grey (double/triple), 35mm4
61015EBond, Molymod, opaque, 2mm (for spacefilling models)11
Synonyms
IUPAC Name: 3-(diaminomethylidene)-1,1-dimethylguanidine , InChI: 1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8) , InChIKey: XZWYZXLIPXDOLR-UHFFFAOYSA-N , SMILES: CN(C)C(=N)N=C(N)N , CAS: 657-24-9 , Glucomine, orabet, diaformin, diamin, glyciphage, dabex, metforal, glibomet, gluformin, riomet, diabetex, diformin, risidon814