Kynurenine

Construct a 3D molecular structure model of Kynurenine using Authentic Molymod Atoms & Bonds by Indigo

Kynurenine is an aromatic α-amino acid derivative as defined by its carboxyl (-COOH) and amino (-NH2) groups and indole-like ring system. It does have the bicyclic structure of its metabolic precursor, the essential amino acid tryptophan.

Kynurenine is a metabolic intermediate in the tryptophan degradation pathway which leads to the production of nicotinamide adenine dinucleotide (NAD), an essential coenzyme in cellular energy metabolism. Tryptophan is converted to N-formylkynurenine by the enzyme indoleamine 2,3-dioxygenase (IDO). N-formylkynurenine then loses its formyl group to yield free kynurenine. Kynurenine branches into several pathways but arguably the most important are the final steps that lead to  NAD. synthesis: 3-Hydroxykynurenine → 3-Hydroxyanthranilic Acid → Quinolinic Acid → NAD, which is critical for cellular respiration, energy metabolism, and DNA repair.

Some sources claim that tryptophan in banana peels can be extracted simply by boiling them & that the "tea" made from the brew can be of help in alleviating issues related to sleep deprivation.

A molecular model of Kynurenine in the Molymod Hybrid Dome style uses the atoms & bonds in the parts list below. Our free 3D Molecular Model Builder shows other styles & allows for image rotation as an assembly guide.

Chemical data
Molecular Weight Chemical Formula
208.2164 C10H12N2O3

Kynurenine molecular model built with Molymod Atoms & Bonds

Hybrid Dome
Open Sphere
Orbit Basic
Orbit Flexible
Parts
Synonyms
IUPAC Name: 2-amino-4-(2-aminophenyl)-4-oxobutanoic acid , InChI=1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15) , InChIKey: YGPSJZOEDVAXAB-UHFFFAOYSA-N , SMILES: C1=CC=C(C(=C1)C(=O)CC(C(=O)O)N)N , C10H12N2O3 , CAS: 343-65-7 , 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid , 2-amino-4-(2-aminophenyl)-4-oxo-butanoic acid , 2-amino-4-(2-aminophenyl)-4-keto-butyric acid , 343-65-7 , 3039-10-9 , Kynurenin , Spectrum4_001916 , 3-(2-aminobenzoyl)-alanine , CHEBI:28683 , SDCCGMLS-0066734.P001 , 61250_FLUKA , EINECS 206-445-9 , SBB005347 , KBio1_001370 , L-KYNURENINE , kynurenine , NCGC00095648-02 , NCGC00095648-01 , SPECTRUM1500879 , SPBio_001340 , KBio3_001702 , (+-)-Kynurenine , Benzenebutanoic acid, alpha,2-diamino-gamma-oxo- , DivK1c_006426 , alpha-2-Diamino-gamma-oxobenzenebutyric acid , Spectrum3_000781 , Spectrum2_001380 , Alanine, 3-anthraniloyl- , Benzenebutanoic acid, .alpha.,2-diamino-.gamma.-oxo- , KBioGR_002539 , 2-Amino-3-(2-aminobenzoyl)propionic acid , KBioSS_001642 , Alanine, 3-anthraniloyl-, DL- , Spectrum_001162 , C01718 , 3-Anthraniloylalanine , Benzenebutanoic acid, .alpha.,2-diamino-.gamma.-oxo-, (S)- , BSPBio_002482 , Spectrum5_000632 , SpecPlus_000330 , Benzenebutanoic acid, alpha,2-diamino-gamma-oxo- (9CI) , (+/-)-Kynurenine , .alpha.-2-diamino-.gamma.-oxobenzenebutyric acid , KBio2_001642 , 2-Amino-4-(2-aminophenyl)-4-oxobutyric acid , KBio2_004210 , Alanine, 3-anthraniloyl- (8CI) , KBio2_006778 , DL-kynurenine