Teach Mendelian genetics with Indigo® PTC taste test strips. Explore TAS2R38 bitter receptor polymorphisms, taster vs. non-taster inheritance, and Hardy-Weinberg class experiments.
Indigo® PTC Taste Test Strips are the classic tool for demonstrating bitter taste genetics through the TAS2R38 receptor. Because PTC sensitivity is controlled largely by a single gene with well-defined PAV/AVI polymorphisms, it remains the most reliable classroom model of Mendelian inheritance, genetic penetrance, and population variation. These strips allow students to identify whether they are strong tasters, medium tasters, or non-tasters and compare class results to the Hardy-Weinberg distribution.
Use Indigo® PTC paper test strips in lab studies of inheritance of taste genotypes, only $3.25 per 100 strips. Compare the chemical structures of PTC (also known as phenylthiourea or phenylthiocarbamide) to that of the simpler thiourea. The phenyl ring in PTC may account for the wider range of taste responses.
PTC strips are used in biology lab experiments to help explain Mendelian Polymorphism and Genetic Penetrance. Document your results to compare where you fall in the Hardy Weinberg distribution.
Phenylthiocarbamide has been used for genetics experiments in biology for over 60 years; if you can taste it, you'll know the moment it touches your tongue.
| Concept | Description | Activity | Learning Link |
|---|---|---|---|
| TAS2R38 Genetics | PTC tasting is governed by a single bitter receptor gene with PAV/AVI polymorphisms. | Compare taster, medium, and non-taster outcomes in class. | Genotype-phenotype relationships; Mendelian patterns. |
| Genetic Penetrance | PTC sensitivity shows clear dominant and recessive expression. | Predict genotype from observed phenotype. | Dominance, penetrance, and allele interaction. |
| Population Genetics | Classroom phenotypes approximate real human allele frequencies. | Calculate Hardy-Weinberg proportions. | Evolution, drift, and selection pressures. |
| Chemosensory Biology | Bitter taste arises from GPCR-based receptors on the tongue. | Discuss receptor-ligand binding and threshold sensitivity. | Structure-function relationships in sensory systems. |
| P/N | Description | QTY |
|---|---|---|
| 33814-TASTE | Taste Strip Combo-PTC, Na Benzoate, Thiorurea, Control | 1 |
Note (1): The number of strips per pack or vial is approximate.
Note (2): Keep out of sunlight.
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